Southeast-Manatee, Part 30, kicks off in about seven hours.
Here is a look at the last five games of the epic series, which Manatee leads 15-14.
2010
When: Sept. 17
Where: John Kiker Memorial Stadium
The score: Manatee 31, Southeast 24
The story: The Hurricanes overcame a 24-7 deficit at the half thanks in part to RB Mike Blakely, who rushed for 150 yards and four touchdowns. Southeast's Brian Poole rushed for 136 yards before he began cramping, and Manatee DB Rhoshaun Goff's interception sealed the win with less than seven seconds remaining. Prior to the pick, a 48-yard reception by Southeast's Calvin Williams that put the ball on Manatee's 25 with a minute remaining was negated when a Noles' lineman was flagged with a personal foul penalty.
They said it: "We were embarassed, but the coaches reassured us that we're a good football team." - Manatee QB Cord Sandberg.
2009
When: Sept. 18
Where: Joe Kinnan Field at Hawkins Stadium
The score: Manatee 30, Southeast 26
The story: Playing in his fourth and final Southeast-Manatee game, Canes QB Brion Carnes scored on a 4-yard run with less than four minutes left to clinch the win. The play was set up by another senior, linebacker Taylor Shipley, who recovered a Southeast fumble on the Noles' 29 with 5:29 left in the game. Carnes ran for two touchdowns, including one that cut Southeast's lead to 26-24 a minute before the fumble, and threw for two. His counterpart, Dyron Speight, threw for 222 yards and three touchdowns to help give Southeast a 20-14 lead at the half.
They said it: "Two good teams...Running up and down the field, having a good time on a Friday night. That's what high school football is all about." - Southeast coach Paul Maecthle.
2008
When: Sept. 19
Where: John Kiker Memorial Stadium
The score: Manatee 16, Southeast 14
The story: Chase Sandberg, a freshman at the time, kicked a 28-yard field goal with just over four minutes remaining to stretch the Hurricanes' lead to 16-7 and its series winning streak to two. It was a vindicating moment for Sandberg, who had missed a point-extra attempt earlier. Manatee was without star running back Ben Axon, who was suspended for a violation of team rules, but got 75 receiving yards from Eric Williams. Southeast's Waymon Bowden scored both of his team's touchdowns.
They said it: "Every year, and I came out here and watched this game and was like, 'Man, I wish I was out there,'" - Sandberg, who served as Manatee's ball boy when he was younger.
2007
When: Sept. 14
Where: Joe Kinnan Field at Hawkins Stadium
The score: Manatee 28, Southeast 16
The story: The Hurricanes beat Southeast for the first time since 2003 and the second time since 1998, and it wasn't easy, as the Noles lead 16-0 after the first quarter and 16-7 at the half. But Manatee took advantage of an early second-half fumble and made the score 16-14 on Ben Axon's 2-yard run. Then, on the first play of the fourth quarter, Manatee receiver Eric Williams turned a 5-yard hitch into a 56-yard touchdown, giving Manatee, which committed five turnovers, all the points it needed.
They said it: "I can't be more proud of the effort they gave in the second half." - Manatee coach Joe Kinnan, who had not defeated the Seminoles since 1998.
2006
When: Aug. 25
Where: John Kiker Memorial Stadium
The score: Southeast 28, Manatee 21
The story: The Seminoles jumped out to a quick 21-6 lead before the game was halted by rain and lightning with 2:21 remaining in the third quarter. The delay lasted over an hour, and when the teams returned, Manatee made it interesting before a Southeast sack sealed the victory for the home team.
They said it: "We were going to try and play it. That's the object. We needed to play." - Manatee coach Joe Kinnan.